Chemistry & Biochemistry Special Seminar: Dr. Gerald Hammond
|Category:||College Of Arts And Sciences|
|Date & Time:||
Thursday , 04/18/2013
from 12:00 PM to 01:00 PM
|Sponsored by:||Chemistry & Biochemistry Deptartment|
Department of Chemistry & Biochemistry Special Seminar
Professor Gerald "G.B." Hammond, University of Louisville
Thursday, April 18th at 12pm, Library-206
All are invited!
Dr. G.B. Hammond, born in Lima, Perú, is a former UMass Dartmouth Professor, now Endowed Chair in Organic Chemistry at University of Louisville in KY. Dr. Hammond received his B.S. from the Pontificia Universidad Catolica del Perú and his Ph.D. from the University of Birmingham. During his 14 years at UMD, Dr. Hammond was a distinguished scholar, receiving the Henry Dreyfus Teacher-Scholar Award, the Dreyfus Scholar-Fellow award, the UMD Scholar of the Year Award, and was a 2003 Fulbright Scholar. Dr. Hammond moved to the University of Louisville in 2004 as Professor of Chemistry and University Scholar. He served as program director in the Chemistry Division at NSF (2007-09) and has held visiting professorships at Harvard, Virginia Tech, Okayama University (Japan), Universidad Nacional Autonoma de Mexico, University of Valencia (Spain), Heidelberg University (Germany) and is adjunct faculty at Universidad Peruana Cayetano Heredia (Peru). In 2011, Dr. Hammond was named Mercator Professor by the DFG, German Research Foundation and received a Career Achievement Award for Outstanding Scholarship, Research, and Creative Activity from the University of Louisville. Professor Hammond's research encompasses new synthetic methodologies, the search for novel uses of fluorine, natural products and drug discovery. Author of 135 publications and 5 patents, he has received over $8 million in grants, and his students have won 30 national and regional awards, and made over 200 international, national, regional and university conference presentations."Is all that glitters gold?"
G.B. Hammond and Bo Xu, Department of Chemistry, University of Louisville
Cationic gold species are viewed as the most powerful catalysts for the electrophilic activation of alkynes/alkenes toward a variety of nucleophiles. But, except for a handful of reactions, a relatively high catalyst loading is needed, and—even in reactions where high turnover or low catalyst loading can be achieved—harsh conditions are required. A rational understanding of ligand effects and additive choices may facilitate the wider adoption of gold catalysis by non-practitioners, who, by far, do not believe that gold is all that glittering. In this presentation, we will provide a clearer understanding of how ligands influence each of the stages of the gold catalytic cycle, and offer a ligand design protocol for selected categories of gold catalyzed reactions. Likewise, we will show that a rational choice of additive may increase the turnover frequency of a reaction in which protodeauration is the rate-determining step and/or the decay of the active catalyst is significant. Furthermore, additives can also act as reactivity modulators to increase chemical yields when the product is labile.