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Bioengineering Seminar |
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| Category: | College of Engineering - BNG |
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| Date & Time: |
Tuesday , 10/09/2012 from 12:30 PM to 01:45 PM |
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| Location: | Tex 102 | |
| Admission: | Free! | |
| Contact: |
Qinguo Fan qinguo.fan@umassd.edu 508-999-9147 |
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| Description: |
Topic: MEMS technologies for mechanical characterization on a single cell level Speaker: Dr. Kidong Park, Postdoctoral Research Associate, University of Illinois at Urbana-Champaign Abstract: This talk will focus on the principle of resonant MEMS mass sensors and their applications in the characterization of mass, growth rate and mechanical stiffness of adherent human colorectal carcinoma cells (HT29) on a single cell level. Single HT29 cells are cultured on the sensor surface and the mass of the target cell was repeatedly measured in a least invasive manner, while the cells are growing on the sensor. The detailed characterization ofthe growth rate confirmed the exponential growth model instead of the linear growth model, which has been of great interest for over 50 years. Also, the stiffness of the cell was extracted by comparing the measured mas of live cells to that of fixed cells. Besides, interesting applications of the developed sensors in physical characterization of micro-scaled objects will be presented. |
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| Additional Info: | Dr. Park and his lab colleagues | |
